袁青梅

教授，博士，硕士生导师

联系方式qmyuan@ynu.edu.cn

教育和工作经历

1. 教育经历：

(1) 2006-09 至 2012-07, 伟德国际1946bv官网, 有机化学, 博士

(2) 1998-09 至 2001-07, 伟德国际1946bv官网, 有机化学, 硕士

(3) 1994-09 至 1998-07, 伟德国际1946bv官网, 应用化学, 学士

2. 工作经历：

(1) 2001-07 至 今, 伟德国际1946bv官网, bevitor伟德国际1946

(2) 2016-06 至 2017-07, 美国宾夕法尼亚州立大学, 生物化学与分子生物学系

研究领域

1. 两亲性多肽的合成和自组装

2. 药物载体的设计合成及疾病诊疗中的应用

3. 微胶囊制备技术及应用研究

4. 高分子水凝胶材料

5. 有机光电材料

科研与教学情况

1.科研项目

（1）一种新型植物毒蛋白--蒜头果蛋白的基因克隆与结构初步分析，国家自然科学基金青年项目。

（2）自修复聚合物材料微胶囊的制备及在基体中的破坏表征，云南省应用基础研究面上项目。

（3）生物农药微胶囊缓释材料，云南省应用基础研究青年项目。

2.教学情况

获得2025年伟德国际1946bv官网“红云园丁教学典范奖”。为本科生开设课程：《大学化学》《高分子材料化学基础》《生物材料学》《有机化学》《无机及分析化学》《高分子材料》，其中《大学化学》和《高分子材料化学基础》为B级课程

主要学术成果

（一）代表性论文

(1) Xiaocui Deng, Zhennan Li, Jingang Yang, Xing Li, Qinming Xu, Gang Li, Qingmei Yuan^*, Epoxy/polymercaptan microcapsules composite: Synthesis, mechanics, and self-healing behavior, Journal of Reinforced Plastics and Composites, 2025, 44(21-22): 2079-2089.

(2) Qinming Xu, Hui Chen, Junming Zhu, Xing Li, Jingang Yang, Xiaocui Deng, Qingmei Yuan^*, Graphene oxide nanosheets conjugated PEG-Glu-Lys-Glu copolymer drug delivery system improves drug loading rates and enables reduction-sensitive drug release and drug tracking, Journal of Biomaterials Science, Polymer Edition, 2024, 35(3).

(3) Xing Li, Zhen Qin, Qingmei Yuan^*, Yadong Song, Qinming Xu, Jingang Yang, Xiaocui Deng, Controllable release of self-assembled reduction-sensitive paclitaxel dimer prodrug and tetrandrine nanoparticles promotes synergistic therapy against multidrug-resistant cancer, Biochimica et Biophysica Acta (BBA) - General Subjects, 2023, 1867(7).

(4) Qinming Xu, Xing Li, Jingang Yang, Yan Zhang, Xiaocui Deng, Gang Li, Qingmei Yuan^*, Naphthyl-Poly(S-((2-carboxyethyl)thio)-l-cysteine) Peptide Amphiphiles with Different Degrees of Polymerization: Synthesis, Self-Assembly, pH/Reduction-Triggered Drug Release, and Cytotoxicity, Molecular Pharmaceutics, 2023, 20(2): 1256-1268.

 (5) Liang Dong, Hui Chen, Ting Liu, Junming Zhu, Min Yu, Qingmei Yuan ^* , Poly(l-cysteine) Peptide Amphiphile Derivatives Containing Disulfide Bonds: Synthesis, Self-Assembly-Inducedβ-Sheet Nanostructures, pH/Reduction Dual Response, and Drug Release, Biomacromolecules, 2021, 22(12): 5374-5381.

（二）授权专利

1. 袁青梅，郑保忠，王兴，杨红卫，一种印楝素微胶囊的悬浮液配方，中国，ZL200510010896.2

Qingmei Yuan

Doctor, Professor, Master student supervisor

Contact information：qmyuan@ynu.edu.cn

Education and Work Experience

1.Education

(1)2006-09 to 2012-07 Yunnan University, Organic Chemistry, PhD

(2)1998-09 to 2001-07, Yunnan University, Organic Chemistry, MA

(3)1994-09 to 1998-07, Yunnan University, Applied Chemistry, BA

2. Work Experience

(1) 2001-07 up to now, School of Materials and Energy, Yunnan University

(2) 2016-06 to 2017-07, Department of Biochemistry and Molecular Biology, Pennsylvania State University, USA

Areas of Concern

1. Synthesis and self-assembly of amphiphilic peptides

2. Design and synthesis of drug carriers and their application in the diagnosis and treatment of cancer and other diseases

3. Preparation and Application of microcapsules

4. Medical polymer materials

5. Organic photoelectric materials

Research and Teaching

1. Research

(1) Gene cloning and structural analysis of a novel plant toxic protein- malanin, National Natural Science Foundation of China,

(2) Preparation and damage characterization of self-healing polymer microcapsules in matrix, Applied Basic Research Surface of Yunnan Province, China

(3) Biopesticide microcapsules sustained-release materials, Youth project of applied basic research in Yunnan Province

2. Teaching

Courses offered: General Chemistry, Polymer material chemistry, Biomaterials Science, Organic chemistry, of which General Chemistry, Polymer material chemistry, are B-level courses.

Academic Achievements

1. Papers

(1) Xiaocui Deng, Zhennan Li, Jingang Yang, Xing Li, Qinming Xu, Gang Li and Qingmei Yuan^*, Epoxy/polymercaptan microcapsules composite: Synthesis, mechanics, and self-healing behavior, Journal of Reinforced Plastics and Composites, 2025, 44(21-22): 2079-2089.

(2) Qinming Xu, Hui Chen, Junming Zhu, Xing Li, Jingang Yang, Xiaocui Deng and Qingmei Yuan^*, Graphene oxide nanosheets conjugated PEG-Glu-Lys-Glu copolymer drug delivery system improves drug loading rates and enables reduction-sensitive drug release and drug tracking, Journal of Biomaterials Science, Polymer Edition, 2024, 35(3).

(3) Xing Li, Zhen Qin, Qingmei Yuan^*, Yadong Song, Qinming Xu, Jingang Yang and Xiaocui Deng, Controllable release of self-assembled reduction-sensitive paclitaxel dimer prodrug and tetrandrine nanoparticles promotes synergistic therapy against multidrug-resistant cancer, Biochimica et Biophysica Acta (BBA) - General Subjects, 2023, 1867(7).

(4) Qinming Xu, Xing Li, Jingang Yang, Yan Zhang, Xiaocui Deng, Gang Li and Qingmei Yuan^*, Naphthyl-Poly(S-((2-carboxyethyl)thio)-l-cysteine) Peptide Amphiphiles with Different Degrees of Polymerization: Synthesis, Self-Assembly, pH/Reduction-Triggered Drug Release, and Cytotoxicity, Molecular Pharmaceutics, 2023, 20(2): 1256-1268.

(5) Liang Dong, Hui Chen, Ting Liu, Junming Zhu, Min Yu and Qingmei Yuan * , Poly(l-cysteine) Peptide Amphiphile Derivatives Containing Disulfide Bonds: Synthesis, Self-Assembly-Inducedβ-Sheet Nanostructures, pH/Reduction Dual Response, and Drug Release, Biomacromolecules, 2021, 22(12): 5374-5381.

2. Patents

(1) Qingmei Yuan, Baozhong Zheng, Xing Wang, Hongwei Yang, A Suspension formulation of azadirachtin microcapsules, 2005-7-7, China, ZL200510010896.2.